21st-century American accordionists

Concetta Rosa Maria Franconero (born December 12, 1937), known professionally as Connie Francis, is an American pop singer, actress, and top-charting female vocalist of the late 1950s and early 1960s. She is estimated to have sold more than 100 million records worldwide.

Charlotte Kemp Muhl (born August 17, 1987), also known simply as Kemp Muhl, is an American singer, songwriter, writer, model and film director from Atlanta, Georgia. Modeling since the age of 13, Muhl at 16 years old became the youngest model to appear on the cover of Britain's Harper's and Queen magazines. Muhl has been in a relationship with Sean Lennon since 2007 and performs with him in the musical duo The Ghost of a Saber Tooth Tiger.

Peter Paul Cetera ( sə-TERR-ə; born September 13, 1944) is an American retired singer, songwriter, and bassist best known for being an original member of the rock band Chicago (1967–1985), before launching a successful solo career. His career as a recording artist encompasses 17 albums with Chicago and eight solo albums.

Alfred Matthew "Weird Al" Yankovic ( YANG-kə-vik; born October 23, 1959) is an American singer, musician, record producer, and actor who is known for humorous songs that make light of pop culture and often parody specific songs by contemporary musical acts. He also performs original songs that are style pastiches of the work of other acts, as well as polka medleys of several popular songs, most of which feature his trademark accordion.

Hunter Easton Hayes (born September 9, 1991) is an American singer, songwriter, record producer, and multi-instrumentalist. He is proficient at more than 30 instruments.

Bruce Randall Hornsby (born November 23, 1954) is an American singer-songwriter and pianist. He draws frequently from classical, jazz, bluegrass, folk, Motown, gospel, rock, blues, and jam band musical traditions.

Daniela Sea (born January 7, 1977) is an American filmmaker, actor and musician. They rose to prominence through their role as Max Sweeney on Showtime's drama series The L Word.

Krist Anthony Novoselic (Croatian: Novoselić; born May 16, 1965) is an American musician and activist. He was the bassist and co-founder of the rock band Nirvana.

Judy Lynn Tenuta (November 7, 1949 – October 6, 2022) was an American comedian, actress, and comedy musician. She was known for her whimsical and brash persona of "The Love Goddess," mixing insult comedy, observational humor, self-promotion, and bawdy onstage antics. Throughout her career, Tenuta built a niche but devoted following, particularly among members of the LGBTQ community. Tenuta wrote two comedy books, and received two Grammy nominations for "Best Comedy Album".

Dennis DeYoung (born February 18, 1947) is an American singer-songwriter, musician and producer. Best known for being a founding member of the rock band Styx as primary lead vocalist and keyboardist, a tenure that lasted from 1970 until June 1999. DeYoung has been credited as the writer of more Styx songs than any other Styx member. He was also the band's most successful writer, penning 7 of the band's 8 Billboard top 10 singles as well as a solo top 10 single.